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|   For many 
                people, the facts about alcoholism are not clear. What is alcoholism, 
                exactly? How does it differ from alcohol abuse? When should a 
                person seek help for a problem related to his or her drinking? 
                The National Institute on Alcohol Abuse and Alcoholism (NIAAA) 
                has prepared this booklet to help individuals and families answer 
                these and other common questions about alcohol problems. The following 
                information explains both alcoholism and alcohol abuse, the symptoms 
                of each, when and where to seek help, treatment choices, and additional 
                helpful resources.  A 
                Widespread Problem For most 
                people who drink, alcohol is a pleasant accompaniment to social 
                activities. Moderate alcohol use—up to two drinks per day 
                for men and one drink per day for women and older people—is 
                not harmful for most adults. (A standard drink is one 12-ounce 
                bottle or can of either beer or wine cooler, one 5-ounce glass 
                of wine, or 1.5 ounces of 80-proof distilled spirits.) Nonetheless, 
                a large number of people get into serious trouble because of their 
                drinking. Currently, nearly 14 million Americans—1 in every 
                13 adults—abuse alcohol or are alcoholic. Several million 
                more adults engage in risky drinking that could lead to alcohol 
                problems. These patterns include binge drinking and heavy drinking 
                on a regular basis. In addition, 53 percent of men and women in 
                the United States report that one or more of their close relatives 
                have a drinking problem. 
                  
                
                
                 The consequences 
                of alcohol misuse are serious—in many cases, life threatening. 
                Heavy drinking can increase the risk for certain cancers, especially 
                those of the liver, esophagus, throat, and larynx (voice box). 
                Heavy drinking can also cause liver cirrhosis, immune system problems, 
                brain damage, and harm to the fetus during pregnancy. In addition, 
                drinking increases the risk of death from automobile crashes as 
                well as recreational and on-the-job injuries. Furthermore, both 
                homicides and suicides are more likely to be committed by persons 
                who have been drinking. In purely economic terms, alcohol-related 
                problems cost society approximately $185 billion per year. In 
                human terms, the costs cannot be calculated.  What 
                Is Alcoholism? Alcoholism, 
                also known as “alcohol dependence,” is a disease that 
                includes four symptoms: • 
                Craving: A strong need, or compulsion, to drink. • 
                Loss of control: The inability to limit one’s drinking 
                on any given occasion. • Physical dependence: Withdrawal symptoms, 
                such as nausea, sweating, shakiness, and anxiety, occur when alcohol 
                use is stopped after a period of heavy drinking. • Tolerance: The need to drink greater 
                amounts of alcohol in order to “get high.” People who are not alcoholic sometimes do not understand why an 
                alcoholic can’t just “use a little willpower” 
                to stop drinking. However, alcoholism has little to do with willpower. 
                Alcoholics are in the grip of a powerful “craving,” 
                or uncontrollable need, for alcohol that overrides their ability 
                to stop drinking. This need can be as strong as the need for food or water. Although 
                some people are able to recover from alcoholism without help, 
                the majority of alcoholics need assistance. With treatment and 
                support, many individuals are able to stop drinking and rebuild 
                their lives. Many people 
                wonder why some individuals can use alcohol without problems but 
                others cannot. One important reason has to do with genetics. Scientists 
                have found that having an alcoholic family member makes it more 
                likely that if you choose to drink you too may develop alcoholism. 
                Genes, however, are not the whole story. In fact, scientists now 
                believe that certain factors in a person’s environment influence 
                whether a person with a genetic risk for alcoholism ever develops 
                the disease. A person’s risk for developing alcoholism can 
                increase based on the person’s environment, including where 
                and how he or she lives; family, friends, and culture; peer pressure; 
                and even how easy it is to get alcohol.  What Is 
                Alcohol Abuse?  Alcohol 
                abuse differs from alcoholism in that it does not include an extremely 
                strong craving for alcohol, loss of control over drinking, or 
                physical dependence. Alcohol abuse is defined as a pattern of 
                drinking that results in one or more of the following situations 
                within a 12-month period:  
                
                  
                
                  
                
                
                 • Failure to fulfill major 
                work, school, or home responsibilities; • Drinking in situations that are physically 
                dangerous, such as while driving a car or operating machinery; • Having recurring alcohol-related legal problems, 
                such as being arrested for driving under the influence of alcohol 
                or for physically hurting someone while drunk; and • Continued drinking despite 
                having ongoing relationship problems that are caused or worsened 
                by the drinking. Although 
                alcohol abuse is basically different from alcoholism, many effects 
                of alcohol abuse are also experienced by alcoholics. What Are 
                the Signs of a Problem? How can 
                you tell whether you may have a drinking problem? Answering the 
                following four questions can help you find out: • 
                Have you ever felt you should cut down on your drinking? • 
                Have people annoyed you by criticizing your drinking? • 
                Have you ever felt bad or guilty about your drinking? • Have you ever had a drink first thing in 
                the morning (as an “eye opener”) to steady your nerves 
                or get rid of a hangover? One “yes” 
                answer suggests a possible alcohol problem. If you answered “yes” 
                to more than one question, it is highly likely that a problem 
                exists. In either case, it is important that you see your doctor 
                or other health care provider right away to discuss your answers 
                to these questions. He or she can help you determine whether you 
                have a drinking problem and, if so, recommend the best course 
                of action. Even if 
                you answered “no” to all of the above questions, if 
                you encounter drinking-related problems with your job, relationships, 
                health, or the law, you should seek professional help. The effects 
                of alcohol abuse can be extremely serious—even fatal—both 
                to you and to others. The Decision To Get Help Accepting 
                the fact that help is needed for an alcohol problem may not be 
                easy. But keep in mind that the sooner you get help, the better 
                are your chances for a successful recovery. Any concerns 
                you may have about discussing drinking-related problems with your 
                health care provider may stem from common misconceptions about 
                alcoholism and alcoholic people. In our society, the myth prevails 
                that an alcohol problem is a sign of moral weakness. As a result, 
                you may feel that to seek help is to admit some type of shameful 
                defect in yourself. In fact, alcoholism is a disease that is no 
                more a sign of weakness than is asthma. Moreover, taking steps 
                to identify a possible drinking problem has an enormous payoff—a 
                chance for a healthier, more rewarding life. When you 
                visit your health care provider, he or she will ask you a number 
                of questions about your alcohol use to determine whether you are 
                having problems related to your drinking. Try to answer these 
                questions as fully and honestly as you can. You also will be given 
                a physical examination. If your health care provider concludes 
                that you may be dependent on alcohol, he or she may recommend 
                that you see a specialist in treating alcoholism. You should be 
                involved in any referral decisions and have all treatment choices 
                explained to you.  Getting Well Alcoholism Treatment The type 
                of treatment you receive depends on the severity of your alcoholism 
                and the resources that are available in your community. Treatment 
                may include detoxification (the process of safely getting alcohol 
                out of your system); taking doctor-prescribed medications, such 
                as disulfiram (Antabuse®) or naltrexone (ReVia™), 
                to help prevent a return (or relapse) to drinking once drinking 
                has stopped; and individual and/or group counseling. There are 
                promising types of counseling that teach alcoholics to identify 
                situations and feelings that trigger the urge to drink and to 
                find new ways to cope that do not include alcohol use. These treatments 
                are often provided on an outpatient basis. Because 
                the support of family members is important to the recovery process, 
                many programs also offer brief marital counseling and family therapy 
                as part of the treatment process. Programs may also link individuals 
                with vital community resources, such as legal assistance, job 
                training, childcare, and parenting classes.   
                
                
                  
                
                  
                
                 Alcoholics Anonymous Virtually 
                all alcoholism treatment programs also include Alcoholics Anonymous 
                (AA) meetings. AA describes itself as a “worldwide fellowship 
                of men and women who help each other to stay sober.” Although 
                AA is generally recognized as an effective mutual help program 
                for recovering alcoholics, not everyone responds to AA’s 
                style or message, and other recovery approaches are available. 
                Even people who are helped by AA usually find that AA works best 
                in combination with other forms of treatment, including counseling 
                and medical care. Can Alcoholism Be Cured? Although 
                alcoholism can be treated, a cure is not yet available. In other 
                words, even if an alcoholic has been sober for a long time and 
                has regained health, he or she remains susceptible to relapse 
                and must continue to avoid all alcoholic beverages. “Cutting 
                down” on drinking doesn’t work; cutting out alcohol 
                is necessary for a successful recovery. However, 
                even individuals who are determined to stay sober may suffer one 
                or several “slips,” or relapses, before achieving 
                long-term sobriety. Relapses are very common and do not mean that 
                a person has failed or cannot recover from alcoholism. Keep in 
                mind, too, that every day that a recovering alcoholic has stayed 
                sober prior to a relapse is extremely valuable time, both to the 
                individual and to his or her family. If a relapse occurs, it is 
                very important to try to stop drinking once again and to get whatever 
                additional support you need to abstain from drinking.  Help for Alcohol Abuse If your 
                health care provider determines that you are not alcohol dependent 
                but are nonetheless involved in a pattern of alcohol abuse, he 
                or she can help you to: • 
                Examine the benefits of stopping an unhealthy drinking pattern. • Set a drinking goal for yourself. Some people 
                choose to abstain from alcohol. Others prefer to limit the amount 
                they drink. • Examine the situations that trigger your 
                unhealthy drinking patterns, and develop new ways of handling 
                those situations so that you can maintain your drinking goal. Some individuals 
                who have stopped drinking after experiencing alcohol-related problems 
                choose to attend AA meetings for information and support, even 
                though they have not been diagnosed as alcoholic. New Directions With NIAAA’s 
                support, scientists at medical centers and universities throughout 
                the country are studying alcoholism. The goal of this research 
                is to develop better ways of treating and preventing alcohol problems. 
                Today, NIAAA funds approximately 90 percent of all alcoholism 
                research in the United States. Some of the more exciting investigations 
                focus on the causes, consequences, treatment, and prevention of 
                alcoholism: • Genetics: Alcoholism is a complex 
                disease. Therefore, there are likely to be many genes involved 
                in increasing a person’s risk for alcoholism. Scientists 
                are searching for these genes, and have found areas on chromosomes 
                where they are probably located. Powerful new techniques may permit 
                researchers to identify and measure the specific contribution 
                of each gene to the complex behaviors associated with heavy drinking. 
                This research will provide the basis for new medications to treat 
                alcohol-related problems. • Treatment:  NIAAA-supported researchers 
                have made considerable progress in evaluating commonly used therapies 
                and in developing new types of therapies to treat alcohol-related 
                problems. One large-scale study sponsored by NIAAA found that 
                each of three commonly used behavioral treatments for alcohol 
                abuse and alcoholism—motivation enhancement therapy, cognitive-behavioral 
                therapy, and 12-step facilitation therapy—significantly 
                reduced drinking in the year following treatment. This study also 
                found that approximately one-third of the study participants who 
                were followed up either were still abstinent or were drinking 
                without serious problems 3 years after the study ended. Other 
                therapies that have been evaluated and found effective in reducing 
                alcohol problems include brief intervention for alcohol abusers 
                (individuals who are not dependent on alcohol) and behavioral 
                marital therapy for married alcohol-dependent individuals.  
                
                
                 • Medications development: NIAAA has made developing 
                medications to treat alcoholism a high priority. We believe that 
                a range of new medications will be developed based on the results 
                of genetic and neuroscience research. In fact, neuroscience research 
                has already led to studies of one medication—naltrexone (ReVia™)—as an anticraving medication.
              NIAAA-supported researchers found that this drug, in combination 
                with behavioral therapy, was effective in treating alcoholism. Naltrexone, which targets the brain’s reward circuits, is 
                the first medication approved to help maintain sobriety after 
                detoxification from alcohol since the approval of disulfiram (Antabuse®) 
                in 1949. The use of acamprosate, an anticraving medication that 
                is widely used in Europe, is based on neuroscience research. Researchers 
                believe that acamprosate works on different brain circuits to 
                ease the physical discomfort that occurs when an alcoholic stops 
                drinking. Acamprosate should be approved for use in the United 
                States in the near future, and other medications are being studied 
                as well. • Combined medications/behavioral therapies: 
              NIAAA-supported researchers have found that available medications 
                work best with behavioral therapy. Thus, NIAAA has initiated a 
                large-scale clinical trial to determine which of the currently 
                available medications and which behavioral therapies work best 
                together. Naltrexone and acamprosate will each be tested separately 
                with different behavioral therapies. These medications will also 
                be used together to determine if there is some interaction between 
                the two that makes the combination more effective than the use 
                of either one alone. In addition 
                to these efforts, NIAAA is sponsoring promising research in other 
                vital areas, such as fetal alcohol syndrome, alcohol’s effects 
                on the brain and other organs, aspects of drinkers’ environments 
                that may contribute to alcohol abuse and alcoholism, strategies 
                to reduce alcohol-related problems, and new treatment techniques. 
                Together, these investigations will help prevent alcohol problems; 
                identify alcohol abuse and alcoholism at earlier stages; and make 
                available new, more effective treatment approaches for individuals 
                and families.  
                
                
                 Resources For more 
                information on alcohol abuse and alcoholism, contact the following 
                organizations: Al-Anon Family Group Headquarters, Inc. 1600 Corporate Landing Parkway Virginia Beach, VA 23454–5617 Phone: (757) 563–1600; Fax: (757) 563–1655 Email: WSO@al-anon.org Internet address: http://www.al-anon.alateen.org Makes referrals 
                to local Al-Anon groups, which are support groups for spouses 
                and other significant adults in an alcoholic person’s life. 
                Also makes referrals to Alateen groups, which offer support to 
                children of alcoholics. Free informational materials and locations 
                of Al-Anon or Alateen meetings worldwide can be obtained by calling 
                the toll-free number (888) 425–2666 from the United States 
                or Canada, Monday through Friday, 8 a.m.–6 p.m. (e.s.t.). Alcoholics Anonymous (AA) World Services, Inc. 475 Riverside Drive, 11th Floor New York, NY 10115 Phone: (212) 870–3400; Fax: (212) 870–3003 Email: via AA’s Web site Internet address: http://www.aa.org Makes referrals 
                to local AA groups and provides informational materials on the 
                AA program. Many cities and towns also have a local AA office 
                listed in the telephone book. All communication should be directed 
                to AA’s mailing address: AA World Services, Inc., Grand 
                Central Station, P.O. Box 459, New York, NY 10163. National Council on Alcoholism and Drug Dependence, Inc. (NCADD) 20 Exchange Place, Suite 2902 New York, NY 10005 Phone: (212) 269–7797; Fax: (212) 269–7510 HOPE LINE: (800) NCA–CALL (24-hour Affiliate referral) Internet address: http://www.ncadd.org Offers educational 
                materials and information on alcoholism. Provides phone numbers 
                of local NCADD Affiliates (who can provide information on local 
                treatment resources) via the above toll-free, 24-hour HOPE LINE. National Institute on Alcohol Abuse and Alcoholism (NIAAA) Scientific Communications Branch 6000 Executive Boulevard,Willco Building, Suite 409 Bethesda, MD 20892–7003 Phone: (301) 443–3860; Fax: (301) 480–1726 Email: niaaaweb-r@exchange.nih.gov Internet address: http://www.niaaa.nih.gov Makes available 
                free informational materials on all aspects of alcoholism, including 
                the effects of drinking during pregnancy, alcohol use and the 
                elderly, and help for cutting down on drinking. 
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